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Caroline O'Sullivan

Caroline O’Sullivan, BSc, MSc
Lecturer
Room: E12
Tel: +353-21-4335886
Email: caroline.osullivan@cit.ie

Caroline graduated with an honours degree in Industrial Chemistry (1998) and completed a masters by research into the ‘In-vitro degradation of poly (butylcyanoacrylate) nanoparticles for drug delivery systems’ in 2001 from University of Limerick. She is currently in the final stages of her PhD on the topic of ‘Novel coatings for hard tissue implants’ from the School of Pharmacy in University College Cork. She has supervised research in the University of South Carolina USA into the areas of biosensors and self assemble models using novel organic /polymer systems (2004). She is a member of the American Chemical Society since 2005. She has worked for four years as a Consultant Scientist for Materials Ireland, serving the pharmaceutical, medical device, food and chemical Industries in Ireland providing solutions to production issues, R&D activities and material analysis.  In addition, she has occupied industrial roles as Senor Research Chemist in Dow Corning Ireland and medical device company EnBIO, conducting research into new product development from bench-top tests to in-vitro and preclinical trials to commercialization (2006-2010).

Teaching

She lectures the following modules:  Formulation (BSc), Biopharmaceutical Processing and BioEngineering (BSc, BEng), Introduction into Microbiology, Organic and Pharmaceutical Chemistry (BEng, BSc), General Chemistry (BSc).

Research Interests

Drug delivery systems, polymer and organic coatings, deposition processes, antimicrobial coatings  to combat MRSA and MSSA infections and novel coatings  for hard tissue implants.

Publications

Books

O’Sullivan C., Desbonnet M., Doyle J. and Hampshire S.  (2003) New Inkjet Printer allows Digital Decoration of Ceramic and Glass in The Irish Scientist Year Book. Geraldine Van Esbeck, Editor.

Patents

EnBio Ltd  (2011) Method for coating medical implants with therapeutic mixtures. US Patent Application 13/254,569.
Carey Brothers Ltd. (2002) Phase change ink composition. Irish Patent Application IE20020020, European Patent Application EP1223201, US Patent Application US6773496.

Peer Reviewed Publications

O’Sullivan C., O’Hare P., Byrne G., O’Neil L.,  Ryan K.B. and Crean A.M., (2011) A modified surface on titanium deposited by a blasting process. Coatings, 1(1), 53-71.
O’Sullivan C., O’Hare  P., O’ Leary N.D., Crean A.M., Ryan K., Dobson A.D.W. and  O’ Neill L. (2010) Deposition of substituted apatites with anti-colonising properties onto titanium surfaces using a novel blasting process. Journal of Biomedical Materials Research Part B 95 (1) 141-149.
O'Neill L., O'Sullivan C., O'Hare P., Sexton L., Keady F. and O'Donoghue J. (2009) Deposition of substituted apatites onto titanium surfaces using a novel blasting process. Surface & Coatings Technology 204, 484-488.
Maynor M.S., Nelson T.L., O'Sullivan C. and Lavigne J.J. (2007) Food freshness sensor using the multistate response from analyte-induced aggregation of a cross-reactive poly(thiophene). Organic Letters 9(17), 3217-3220.
Nelson T.L., O’Sullivan C., Green N.T., Maynor M. and Lavigne J.J. (2006) Cross-Reactive Conjugated Polymers: Analyte-Specific Aggregative Response for Structurally Similar Diamines. Journal of the American Chemical Society 128, 5640-5641. 
Niu W., O’ Sullivan C., Rambo B. M., Smith M.D., Lavigne J.J.  (2005) Self-Repairing polymers: Poly(dioxaborolane)s containing Trigonal Planar Boron.  Chemical Communications 34, 4342-4344.
O’Sullivan C.  and Birkinshaw C. (2004) In-vitro degradation of insulin loaded poly (n-butyl cyanoacrylate) nanoparticles. Biomaterials 25, 4375-4375.
O’Sullivan C. and Birkinshaw C. (2002) Hydrolysis of poly (n-butylcyanoacrylate) nanoparticles using esterase. Polymer Degradation and Stability 78, 7-15.

Non Peer Reviewed Publications

Nelson T., O’Sullivan C. and Lavigne J.J. (2006) Conjugated polymer assembly: a unique approach to small molecule sensing. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry)  47(1),  89.
Lavigne J.J., Nelson T. L and O' Sullivan C. (2004) Combinatorial Approach to Small Molecule Directed Self-Assembly of Poly (thiophene)s Towards Generating Optical Materials.  Polymeric Materials Science and Engineering 90, 722.

Conference Papers

Nelson T., O’Sullivan C. and Lavigne J.J. (2006) Conjugated polymer assembly: a unique approach to small molecule sensing. Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006  (2006).
Lavigne J. J., Broughton D.L., O'Sullivan C., Nelson T. L. and Bunz U. H.  (2005) Conjugated Polymer Biosensors’ Abstracts of papers. Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17.
Lavigne J.J., O'Sullivan C., Maynor M. (2004) Combinatorial Approach to the Metal Mediated Self-Assembly of Poly (thiophene)s’   Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1.
Lavigne J.J., Nelson T. L and O' Sullivan C. (2004) Combinatorial Approach to Small Molecule Directed Self-Assembly of Poly (thiophene)s Towards Generating Optical Materials Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1.

Oral Presentations

O’ Sullivan C. (2011) In at the Deep End: Learning to Teach in Higher Education-Lost in Translation.  Postgraduate Symposium, University College Cork, Cork, February 16.
O’ Sullivan C., Crean A. and Ryan K. (2010) Novel Coatings for Hard Tissue Implants. Joint Schools of Pharmacy Research Seminar.  Queens University of Belfast, Belfast, March 29-30  .
O’ Sullivan C., Crean A. and Ryan K. (2010) Novel Coatings for Hard Tissue Implants.  School of Pharmacy Research Seminar.  University College Cork, Cork, January 29.

Poster Presentations

O’ Sullivan C., Crean A. and Ryan K. (2010) The Use of Substituted Apatites to Combat Bacterial Infections on Hard Tissue Implants. Poster presentation at Molecules to Medicine Research Conference, College of Medicine & Health, UCC, June 16.

O’ Sullivan C., Crean A. and Ryan K. (2011) The Use of Substituted Apatites to Combat Bacterial Infections on Hard Tissue Implants. Poster presentation at PhD Reaserch Day, School of Pharmacy, UCC, September 15.

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